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3114 Investigating the therapeutic potential of parthenolide in the treatment of hematopoietic neoplasms in dogs

OBJECTIVES/SPECIFIC AIMS: Determine PTL’s mechanism(s) of action in a panel of canine hematopoietic cell lines; this will enable us to 1) verify that PTL is working as expected and 2) rationally select combination therapeutics. Characterize the in vitro sensitivity of canine hematopoietic cell lines...

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Detalles Bibliográficos
Autores principales:	Schlein, Lisa J, Peterson, Aubree, Rose, Barbara, Thamm, Douglas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2019
Materias:	Basic/Translational Science/Team Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799165/ http://dx.doi.org/10.1017/cts.2019.37

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