3174 Tumor suppressors p53 and ARF control oncogenic potential of triple-negative breast cancer cells by regulating RNA editing enzyme ADAR1

OBJECTIVES/SPECIFIC AIMS: Triple-negative breast cancer (TNBC) accounts for one-fifth of the breast cancer patient population. The heterogeneous nature of TNBC and lack of options for targeted therapy make its treatment a constant challenge. The co-deficiency of tumor suppressors p53 and ARF is a si...

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Detalles Bibliográficos
Autores principales: Kung, Che-Pei, Bross, Emily, Bramel, Emily, Freeman, Eric, Sabloak, Thwisha, Kuzmicki, Catherine, Benjamin, Mike, Maggi, Leonard, Weber, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2019
Materias:
Basic/Translational Science/Team Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799193/
http://dx.doi.org/10.1017/cts.2019.61

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