Cargando…

3204 Renin-Angiotensin System Inhibitors Do Not Improve Survival in Fibrillin-1 Hypomorphic Mice with Established Aortic Aneurysm

OBJECTIVES/SPECIFIC AIMS: Drugs to attenuate aortic growth are usually not initiated in patients with Marfan syndrome until aortic dilation is already present. Therefore, we measured the impact of drugs (the renin-angiotensin system inhibitors losartan and enalapril) on survival and thoracic aortic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sheppard, Mary Burchett, Chen, Jeff Zheying, Rateri, Debra L., Moorleghen, Jessica J., Weiland, Mackenzie, Daugherty, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2019
Materias:	Mechanistic Basic to Clinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799274/ http://dx.doi.org/10.1017/cts.2019.258

Ejemplares similares

Aortic Strain Correlates With Elastin Fragmentation in Fibrillin-1 Hypomorphic Mice
por: Chen, Jeff Z., et al.
Publicado: (2019)

Doxycycline Does Not Influence Established Abdominal Aortic Aneurysms in Angiotensin II-Infused Mice
por: Xie, Xiaojie, et al.
Publicado: (2012)

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
por: Lu, Hong, et al.
Publicado: (2015)

Transforming Growth Factor‐β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant?
por: Daugherty, Alan, et al.
Publicado: (2017)

10061 Assessing immunogenicity of an Ebola vaccine in humans using a systems biology approach
por: Martin, Olivia, et al.
Publicado: (2021)

Depletion of Endothelial or Smooth Muscle Cell-Specific Angiotensin II Type 1a Receptors Does Not Influence Aortic Aneurysms or Atherosclerosis in LDL Receptor Deficient Mice
por: Rateri, Debra L., et al.
Publicado: (2012)

30143 Asymptomatic Thoracic Aortic Aneurysm Growth Rates and Predicting Factors: A Systematic Review and Meta-Analysis
por: Henry, Matthew, et al.
Publicado: (2021)

2464 Sexual dimorphism in a mouse model of syndromic thoracic aortic aneurysm
por: Chen, Zheying, et al.
Publicado: (2018)

Renin-Angiotensin System and Cardiovascular Functions
por: Wu, Chia-Hua, et al.
Publicado: (2018)

2529: Clinical determinants of clopidogrel responsiveness in a heterogeneous cohort of Caribbean Hispanics
por: Suarez, Dagmar Fredy Hernandez, et al.
Publicado: (2018)

2519: A quantitative disintegration method to evaluate polymeric films
por: Grab, Sheila, et al.
Publicado: (2018)

2370: Understanding epicardial fat biology by imaging
por: Stojanovska, Jadranka, et al.
Publicado: (2018)

3089 Clinicopathologic and Prognostic Significance of LGR5, a Cancer Stem cell Marker in Peritoneal Metastasis of a Colorectal Origin
por: Ihemelandu, Chukwuemeka
Publicado: (2019)

3280 Mycobacterium bovis Bacille-Calmette-Guérin infection aggravates atherosclerosis
por: Huaman, Moises, et al.
Publicado: (2019)

3332 Overexpression of CD44 is involved in the development of the early endometriotic lesion in a xenograft model
por: Knudtson, Jennifer, et al.
Publicado: (2019)

3127 The effect of common genetic variants in the oxytocin receptor gene on oxytocin response.
por: Malik, Manasi, et al.
Publicado: (2019)

2064: Deconstructing the peptide specificity of TCR recognition
por: Riley, Timothy P., et al.
Publicado: (2018)

3496 Mesenchymal Stem Cell Extracellular Vesicle Delivery in a Shear-Thinning Hydrogel For Therapy in an Acute Myocardial Infarction Model: A Comparative Analysis
por: Goldberg, Drew, et al.
Publicado: (2019)

3379 Associations between Diabetes Mellitus and Sublingual Microvascular Disease: A Prospective Cross-Sectional Study
por: Smilowitz, Nathaniel R, et al.
Publicado: (2019)

3559 Mechanisms of sebaceous skin microbial community remodeling through microenvironment modulation.
por: McCoy, William Howard, et al.
Publicado: (2019)

3268 A TL1 Team Approach to Personalizing Donor Human Milk for the Preterm Infant
por: Bendixen, Marion M, et al.
Publicado: (2019)

3285 Toxicity of Released B Cell Products in Multiple Sclerosis: Effects on Neurons and Oligodendrocytes
por: Zuroff, Leah, et al.
Publicado: (2019)

3424 Serial Biomarker Monitoring Predicts Long Term Outcomes in Acute Graft Versus Host Disease
por: Srinagesh, Hrishikesh Krishna, et al.
Publicado: (2019)

2399: Protective immunity to live vaccines among children with solid tumors
por: Garcia Robles, Franchesca, et al.
Publicado: (2018)

3024 Osteocyte-derived CXCL12 is Essential for Load-Induced Bone Formation in Adult Mice
por: Zuckerman, Pamela Cabahug, et al.
Publicado: (2019)

2097: Aging-associated increases in platelet granzyme A regulate pro-inflammatory gene synthesis by monocytes
por: Thomas Rondina, Matthew, et al.
Publicado: (2018)

3019 Metabolomic Markers of Methotrexate Response in Juvenile Idiopathic Arthritis
por: Funk, Ryan Sol, et al.
Publicado: (2019)

2188: Implanted multijoint functional electrical stimulation assistance improves walking efficiency after stroke: A case report
por: Makowski, Nathaniel, et al.
Publicado: (2018)

3296 Endometrial cancer microbiome biomarker for disease detection and microbial role in the disease
por: Walther-Antonio, Marina, et al.
Publicado: (2019)

2485: ETV6 represses Pax5 in early B-cell development
por: Kirkpatrick, Greg, et al.
Publicado: (2018)

3160 The Effects of Aging on the Rectal Mucosal CD4+ T cell Compartment and its Implications for HIV Transmission
por: Ackerley, Cassie Grimsley, et al.
Publicado: (2019)

2080: Therapeutic potential of mesenchymal stromal cells for hypoxic ischemic encephalopathy: A systematic review of preclinical studies
por: Moreira, Alvaro, et al.
Publicado: (2018)

2371: Perception- and behavior-related attention systems distinguished by phase amplitude coupling and high-gamma power
por: Varkki Chacko, Ravi, et al.
Publicado: (2018)

2367: Defining critical features of the immune microenvironment in melanoma using multiplex immunohistochemistry and spatial analysis
por: Gartrell, Robyn, et al.
Publicado: (2018)

3122 Longitudinal Recovery of Speech Motor Function Following Facial Transplantation
por: Perry, Bridget Jane, et al.
Publicado: (2019)

2392: Detecting cardiometabolic disease through breath analysis: A metabolomic approach
por: Choudary, Ahsan, et al.
Publicado: (2018)

3278 Gendered racism, psychological distress, and the strong Black woman
por: Baalbaki, Maha
Publicado: (2019)

3477 Impaired emotion recognition accuracy after right-hemisphere stroke
por: OConnell, Katherine, et al.
Publicado: (2019)

2180: hnRNP K overexpression drives acute myeloid leukemia emergence and progression
por: Hornbaker, Marisa, et al.
Publicado: (2018)

2114: The role of estrogen receptor-β in the development of the early endometriotic lesion
por: Knudtson, Jennifer, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_uu2jkk63f1pfqesj0292jreg68