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2525 Development of human cell-based screening assays to detect subject-specific drug-response variability

OBJECTIVES/SPECIFIC AIMS: The goals of this study are to develop a human-based screening assay for testing individual drug reactions and investigate the mechanism underlying susceptibility to develop diLQT. METHODS/STUDY POPULATION: We derived iPSC-CMs from 10 subjects with a high sensitivity to Sot...

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Detalles Bibliográficos
Autores principales:	Stillitano, Francesca, Mayourian, Joshua, Dave, Jaydev, Hulot, Jean-Sébastien, Hajjar, Roger J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2018
Materias:	Basic/Translational Science/Team Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799307/ http://dx.doi.org/10.1017/cts.2018.64

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