2559 Role of tissue non-specific alkaline phosphatase (TNAP) in promoting the survival of acute myeloid leukemia (AML) cells within the bone marrow microenvironment

OBJECTIVES/SPECIFIC AIMS: Treatment of acute myeloid leukemia (AML) is challenging, as apoptosis-resistant AML cells often persist within the bone marrow microenvironment despite chemotherapy. The overall goal of our laboratory is to identify and ultimately target the bone marrow factors that protec...

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Detalles Bibliográficos
Autores principales: Bowles, Bradley, Sterner, Rosalie M., Kremer, Kimberly N., Dudakovic, Amel, Westendorf, Jennifer J., Van Wijnen, Andre J., Hedin, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Basic/Translational Science/Team Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799340/
http://dx.doi.org/10.1017/cts.2018.119

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