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2028 Discovery and evaluation of FOXP3 dimerization inhibitors

OBJECTIVES/SPECIFIC AIMS: Immuno-oncology (IO) strategies are promising new approaches for the treatment of a variety of malignancies, including multiple myeloma (MM). Regulatory T cells (Tregs), which suppress effector T cell function, are a limitation to durable IO responses. The transcription fac...

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Detalles Bibliográficos
Autores principales:	Thompson, Ravyn, Coleman, Cara, Dolloff, Nathan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2018
Materias:	Basic/Translational Science/Team Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799343/ http://dx.doi.org/10.1017/cts.2018.65

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