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2461 Increasing butyrate levels by microbial manipulation or drug administration to delay Parkinson’s disease progression

OBJECTIVES/SPECIFIC AIMS: Determine if synthetic or endogenously produced butyrate can delay Parkinson’s disease (PD) progression, attenuate PD associated GI dysfunction, and impact the gut-microbiota in mice expressing human mutant aSyn. METHODS/STUDY POPULATION: Two transgenic mouse models express...

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Detalles Bibliográficos
Autores principales:	Garcia, Stephanie M., Zhou, Wenbo, Freed, Curt R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2018
Materias:	Basic/Translational Science/Team Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799473/ http://dx.doi.org/10.1017/cts.2018.86

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