miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation

Activation of microglia and the subsequently elevated inflammatory cytokine release in the brain during surgery predispose individuals to cognitive dysfunction, also known as postoperative cognitive dysfunction (POCD). miR-124 is one of the most abundant microRNAs in the brain that regulates microgl...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Sun, Jing-xian, Chen, Wan-kun, Wu, Gen-cheng, Wang, Yan-qing, Zhu, Ke-ying, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799846/
https://www.ncbi.nlm.nih.gov/pubmed/31637007
http://dx.doi.org/10.1038/s41392-019-0061-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799846/
https://www.ncbi.nlm.nih.gov/pubmed/31637007
http://dx.doi.org/10.1038/s41392-019-0061-x

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