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miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation
Activation of microglia and the subsequently elevated inflammatory cytokine release in the brain during surgery predispose individuals to cognitive dysfunction, also known as postoperative cognitive dysfunction (POCD). miR-124 is one of the most abundant microRNAs in the brain that regulates microgl...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799846/ https://www.ncbi.nlm.nih.gov/pubmed/31637007 http://dx.doi.org/10.1038/s41392-019-0061-x |