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Toward point-of-care assessment of patient response: a portable tool for rapidly assessing cancer drug efficacy using multifrequency impedance cytometry and supervised machine learning
We present a novel method to rapidly assess drug efficacy in targeted cancer therapy, where antineoplastic agents are conjugated to antibodies targeting surface markers on tumor cells. We have fabricated and characterized a device capable of rapidly assessing tumor cell sensitivity to drugs using mu...
Autores principales: | Ahuja, Karan, Rather, Gulam M., Lin, Zhongtian, Sui, Jianye, Xie, Pengfei, Le, Tuan, Bertino, Joseph R., Javanmard, Mehdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799891/ https://www.ncbi.nlm.nih.gov/pubmed/31645995 http://dx.doi.org/10.1038/s41378-019-0073-2 |
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