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Hypoxia-Induced Cleavage Of Soluble ephrinA1 From Cancer Cells Is Mediated By MMP-2 And Associates With Angiogenesis In Oral Squamous Cell Carcinoma

INTRODUCTION: ephrinA1 plays important roles in tumor angiogenesis. Matrix metalloproteases (MMPs) can cleave ephrinA1 from the cell membrane into extracellular environment. However, how soluble ephrinA1 is modulated by hypoxia and whether MMPs participate in this hypoxic process remains to be inves...

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Detalles Bibliográficos
Autores principales:	Ma, Ting-Ting, Wang, Lin, Wang, Jun-Lin, Liu, Yan-Jie, Chen, Yu-Cong, He, Hu-Jie, Song, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799903/ https://www.ncbi.nlm.nih.gov/pubmed/31686863 http://dx.doi.org/10.2147/OTT.S213252

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