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Cisd2 is essential to delaying cardiac aging and to maintaining heart functions

CDGSH iron-sulfur domain-containing protein 2 (Cisd2) is pivotal to mitochondrial integrity and intracellular Ca(2+) homeostasis. In the heart of Cisd2 knockout mice, Cisd2 deficiency causes intercalated disc defects and leads to degeneration of the mitochondria and sarcomeres, thereby impairing its...

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Detalles Bibliográficos
Autores principales:	Yeh, Chi-Hsiao, Shen, Zhao-Qing, Hsiung, Shao-Yu, Wu, Pei-Chun, Teng, Yuan-Chi, Chou, Yi-Ju, Fang, Su-Wen, Chen, Chian-Feng, Yan, Yu-Ting, Kao, Lung-Sen, Kao, Cheng-Heng, Tsai, Ting-Fen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799937/ https://www.ncbi.nlm.nih.gov/pubmed/31593566 http://dx.doi.org/10.1371/journal.pbio.3000508

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