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Conformational flexibility of fork-remodeling helicase Rad5 shown by full-ensemble hybrid methods
Several pathways exist to bypass DNA damage during replication. One such pathway is template switching. The Rad5 protein plays two important roles in template switching: it is an E3 ubiquitin ligase that catalyzes PCNA poly-ubiquitylation and it is a helicase that converts replication forks to chick...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799953/ https://www.ncbi.nlm.nih.gov/pubmed/31626633 http://dx.doi.org/10.1371/journal.pone.0223875 |