A single regulator NrtR controls bacterial NAD(+) homeostasis via its acetylation

Nicotinamide adenine dinucleotide (NAD(+)) is an indispensable cofactor in all domains of life, and its homeostasis must be regulated tightly. Here we report that a Nudix-related transcriptional factor, designated MsNrtR (MSMEG_3198), controls the de novo pathway of NAD(+)biosynthesis in M. smegmati...

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Detalles Bibliográficos
Autores principales: Gao, Rongsui, Wei, Wenhui, Hassan, Bachar H, Li, Jun, Deng, Jiaoyu, Feng, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800001/
https://www.ncbi.nlm.nih.gov/pubmed/31596237
http://dx.doi.org/10.7554/eLife.51603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800001/
https://www.ncbi.nlm.nih.gov/pubmed/31596237
http://dx.doi.org/10.7554/eLife.51603

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