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A single regulator NrtR controls bacterial NAD(+) homeostasis via its acetylation

Nicotinamide adenine dinucleotide (NAD(+)) is an indispensable cofactor in all domains of life, and its homeostasis must be regulated tightly. Here we report that a Nudix-related transcriptional factor, designated MsNrtR (MSMEG_3198), controls the de novo pathway of NAD(+)biosynthesis in M. smegmati...

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Detalles Bibliográficos
Autores principales:	Gao, Rongsui, Wei, Wenhui, Hassan, Bachar H, Li, Jun, Deng, Jiaoyu, Feng, Youjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800001/ https://www.ncbi.nlm.nih.gov/pubmed/31596237 http://dx.doi.org/10.7554/eLife.51603

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