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Epigenetic silencing of HOPX is critically involved in aggressive phenotypes and patient prognosis in papillary thyroid cancer

HOPX is involved in multiple organ development and acts as a tumor suppressor in various cancers. Epigenetic silencing of HOPX via its promoter methylation has been shown frequent and cancer-specific in human cancers. The proliferation of thyroid cancer cells and cancer progression are strongly infl...

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Detalles Bibliográficos
Autores principales:	Ooizumi, Yosuke, Katoh, Hiroshi, Yokota, Mitsuo, Watanabe, Masahiko, Yamashita, Keishi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800262/ https://www.ncbi.nlm.nih.gov/pubmed/31666923 http://dx.doi.org/10.18632/oncotarget.27187

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