A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation

Patients with multiple myeloma often show skull bone involvement, although in most cases this is manifested as skull erosion and large masses develop only rarely. Here we report a patient who presented with a large cranial mass mimicking a subdural hematoma with calcification. The tumor shrunk with...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujimaki, Takamitsu, Hirata, Sachiko, Terano, Naruhiko, Wakiya, Kenji, Kobayashi, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800278/
https://www.ncbi.nlm.nih.gov/pubmed/31637287
http://dx.doi.org/10.1055/s-0039-1697636
_version_ 1783460417655275520
author Fujimaki, Takamitsu
Hirata, Sachiko
Terano, Naruhiko
Wakiya, Kenji
Kobayashi, Masahito
author_facet Fujimaki, Takamitsu
Hirata, Sachiko
Terano, Naruhiko
Wakiya, Kenji
Kobayashi, Masahito
author_sort Fujimaki, Takamitsu
collection PubMed
description Patients with multiple myeloma often show skull bone involvement, although in most cases this is manifested as skull erosion and large masses develop only rarely. Here we report a patient who presented with a large cranial mass mimicking a subdural hematoma with calcification. The tumor shrunk with 37.5 Gy of focal irradiation in 15 fractions after biopsy. After irradiation the patient was treated with Bortezomib but died because of adverse events. The differential diagnosis of lenticular lesion of the skull and treatment strategy for large skull mass with myeloma cells are discussed.
format Online
Article
Text
id pubmed-6800278
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Thieme Medical Publishers
record_format MEDLINE/PubMed
spelling pubmed-68002782019-10-21 A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation Fujimaki, Takamitsu Hirata, Sachiko Terano, Naruhiko Wakiya, Kenji Kobayashi, Masahito Surg J (N Y) Patients with multiple myeloma often show skull bone involvement, although in most cases this is manifested as skull erosion and large masses develop only rarely. Here we report a patient who presented with a large cranial mass mimicking a subdural hematoma with calcification. The tumor shrunk with 37.5 Gy of focal irradiation in 15 fractions after biopsy. After irradiation the patient was treated with Bortezomib but died because of adverse events. The differential diagnosis of lenticular lesion of the skull and treatment strategy for large skull mass with myeloma cells are discussed. Thieme Medical Publishers 2019-10-18 /pmc/articles/PMC6800278/ /pubmed/31637287 http://dx.doi.org/10.1055/s-0039-1697636 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Fujimaki, Takamitsu
Hirata, Sachiko
Terano, Naruhiko
Wakiya, Kenji
Kobayashi, Masahito
A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation
title A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation
title_full A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation
title_fullStr A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation
title_full_unstemmed A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation
title_short A Large Mass Mimicking Calcified Hematoma of the Skull Showing Involvement of Myeloma Cells and a Good Response to Irradiation
title_sort large mass mimicking calcified hematoma of the skull showing involvement of myeloma cells and a good response to irradiation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800278/
https://www.ncbi.nlm.nih.gov/pubmed/31637287
http://dx.doi.org/10.1055/s-0039-1697636
work_keys_str_mv AT fujimakitakamitsu alargemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT hiratasachiko alargemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT teranonaruhiko alargemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT wakiyakenji alargemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT kobayashimasahito alargemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT fujimakitakamitsu largemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT hiratasachiko largemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT teranonaruhiko largemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT wakiyakenji largemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation
AT kobayashimasahito largemassmimickingcalcifiedhematomaoftheskullshowinginvolvementofmyelomacellsandagoodresponsetoirradiation

Ejemplares similares