In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN

Bipolar disorder (BP) and schizophrenia (SCZ) are major psychiatric disorders, but the molecular mechanisms underlying the complicated pathologies of these disorders remain unclear. It is difficult to establish adequate in vitro models for pathological analysis because of the heterogeneity of these...

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Detalles Bibliográficos
Autores principales: Ishii, Takaya, Ishikawa, Mitsuru, Fujimori, Koki, Maeda, Takuji, Kushima, Itaru, Arioka, Yuko, Mori, Daisuke, Nakatake, Yuhki, Yamagata, Bun, Nio, Shintaro, Kato, Takahiro A., Yang, Nan, Wernig, Marius, Kanba, Shigenobu, Mimura, Masaru, Ozaki, Norio, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800292/
https://www.ncbi.nlm.nih.gov/pubmed/31540999
http://dx.doi.org/10.1523/ENEURO.0403-18.2019

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