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Madin‐Darby canine kidney cell sialic acid receptor modulation induced by culture medium conditions: Implications for the isolation of influenza A virus

BACKGROUND: The influenza A virus (IAV) binds to α‐2,3‐ and α‐2,6‐linked sialic acid (SA) receptors expressed by Madin‐Darby canine kidney (MDCK) cells. The receptor distribution may therefore be important in regulating IAV propagation. Serum‐free medium (SFM) avoids variability in conventional cult...

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Detalles Bibliográficos
Autores principales: Nelson, Sarah W., Lorbach, Joshua N., Nolting, Jacqueline M., Stull, Jason W., Jackwood, Daral J., Davis, Ian C., Bowman, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800301/
https://www.ncbi.nlm.nih.gov/pubmed/31392833
http://dx.doi.org/10.1111/irv.12671