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Coupling Multi-Angle Light Scattering to Reverse-Phase Ultra-High-Pressure Chromatography (RP-UPLC-MALS) for the characterization monoclonal antibodies

Multi-angle light scattering coupled with size-exclusion chromatography (SEC-MALS) is a standard approach for protein characterization. Recently MALS detection has been coupled with ion-exchange chromatography (IEX) which demonstrated the feasibility and high value of MALS in combination with non-si...

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Detalles Bibliográficos
Autores principales:	Gentiluomo, Lorenzo, Schneider, Vanessa, Roessner, Dierk, Frieß, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800455/ https://www.ncbi.nlm.nih.gov/pubmed/31628369 http://dx.doi.org/10.1038/s41598-019-51233-6

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