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DOT1L complex suppresses transcription from enhancer elements and ectopic RNAi in Caenorhabditis elegans

Methylation of histone H3 on lysine 79 (H3K79) by DOT1L is associated with actively transcribed genes. Earlier, we described that DOT-1.1, the Caenorhabditis elegans homolog of mammalian DOT1L, cooperates with the chromatin-binding protein ZFP-1 (AF10 homolog) to negatively modulate transcription of...

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Detalles Bibliográficos
Autores principales:	Esse, Ruben, Gushchanskaia, Ekaterina S., Lord, Avery, Grishok, Alla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800474/ https://www.ncbi.nlm.nih.gov/pubmed/31300558 http://dx.doi.org/10.1261/rna.070292.119

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