Pairing interactions between nucleobases and ligands in aptamer:ligand complexes of riboswitches: crystal structure analysis, classification, optimal structures, and accurate interaction energies

In the present work, 67 crystal structures of the aptamer domains of RNA riboswitches are chosen for analysis of the structure and strength of hydrogen bonding (pairing) interactions between nucleobases constituting the aptamer binding pockets and the bound ligands. A total of 80 unique base:ligand...

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Detalles Bibliográficos
Autores principales: Seelam, Preethi P., Mitra, Abhijit, Sharma, Purshotam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800475/
https://www.ncbi.nlm.nih.gov/pubmed/31315914
http://dx.doi.org/10.1261/rna.071530.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800475/
https://www.ncbi.nlm.nih.gov/pubmed/31315914
http://dx.doi.org/10.1261/rna.071530.119

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