Cargando…

RNAscope in situ hybridization-based method for detecting DUX4 RNA expression in vitro

Facioscapulohumeral muscular dystrophy (FSHD) is among the most common forms of muscular dystrophy. FSHD is caused by aberrant expression of the toxic DUX4 gene in muscle. Detecting endogenous DUX4 in patient tissue using conventional methods can be challenging, due to the low level of DUX4 expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Amini Chermahini, Gholamhossein, Rashnonejad, Afrooz, Harper, Scott Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800509/
https://www.ncbi.nlm.nih.gov/pubmed/31209064
http://dx.doi.org/10.1261/rna.070177.118