Efficient electroporation of neuronal cells using synthetic oligonucleotides: identifying duplex RNA and antisense oligonucleotide activators of human frataxin expression

Oligonucleotide drugs are experiencing greater success in the clinic, encouraging the initiation of new projects. Resources are insufficient to develop every potentially important project, and persuasive experimental data using cell lines close to disease target tissue is needed to prioritize candid...

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Detalles Bibliográficos
Autores principales: Shen, Xiulong, Beasley, Sharon, Putman, Jennifer N., Li, Yanjie, Prakash, Thahza P., Rigo, Frank, Napierala, Marek, Corey, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800520/
https://www.ncbi.nlm.nih.gov/pubmed/31151992
http://dx.doi.org/10.1261/rna.071290.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800520/
https://www.ncbi.nlm.nih.gov/pubmed/31151992
http://dx.doi.org/10.1261/rna.071290.119

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