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Efficient electroporation of neuronal cells using synthetic oligonucleotides: identifying duplex RNA and antisense oligonucleotide activators of human frataxin expression
Oligonucleotide drugs are experiencing greater success in the clinic, encouraging the initiation of new projects. Resources are insufficient to develop every potentially important project, and persuasive experimental data using cell lines close to disease target tissue is needed to prioritize candid...
Autores principales: | Shen, Xiulong, Beasley, Sharon, Putman, Jennifer N., Li, Yanjie, Prakash, Thahza P., Rigo, Frank, Napierala, Marek, Corey, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800520/ https://www.ncbi.nlm.nih.gov/pubmed/31151992 http://dx.doi.org/10.1261/rna.071290.119 |
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