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BIRC5 Gene Disruption via CRISPR/Cas9n Platform Suppress Acute Myelocytic Leukemia Progression

BACKGROUND: Acute myelocytic leukemia (AML) is a clonal malignancy resulting from the accumulation of genetic abnormalities in the cells. Human baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5), encodes survivin, is one of only a handful of genes that is differentially over-expressed in...

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Detalles Bibliográficos
Autores principales:	Narimani, Manizheh, Sharifi, Mohammadreza, Hakhamaneshi, Mohammad Saeed, Roshani, Daem, Kazemi, Mohammad, Hejazi, Seyed Hossein, Jalili, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pasteur Institute of Iran 2019
Materias:	Full Length
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800533/ https://www.ncbi.nlm.nih.gov/pubmed/31104397 http://dx.doi.org/10.29252/ibj.23.6.369

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