Soluble epoxide hydrolase inhibition enhances anti-inflammatory and antioxidative processes, modulates microglia polarization, and promotes recovery after ischemic stroke

BACKGROUND: Ischemic stroke triggers inflammatory responses and oxidative stress in the brain, and microglia polarization affects the degree of neuroinflammation. It has been reported that the inhibition of soluble epoxide hydrolase (sEH) activity protects brain tissue. However, the anti-inflammator...

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Detalles Bibliográficos
Autores principales: Yeh, Chien-Fu, Chuang, Tung‐Yueh, Hung, Yu-Wen, Lan, Ming-Ying, Tsai, Ching-Han, Huang, Hao-Xiang, Lin, Yung-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800549/
https://www.ncbi.nlm.nih.gov/pubmed/31686827
http://dx.doi.org/10.2147/NDT.S210403

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