Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications

Among the various nano/biomaterials used in cancer treatment, the beauty and benefits of DNA nanocomposites are outstanding. The specificity and programmability of the base pairing of DNA strands, together with their ability to conjugate with different types of functionalities have realized unsurpas...

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Autores principales: Jahanban-Esfahlan, Rana, Seidi, Khaled, Jahanban-Esfahlan, Ali, Jaymand, Mehdi, Alizadeh, Effat, Majdi, Hasan, Najjar, Reza, Javaheri, Tahereh, Zare, Peyman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800557/
https://www.ncbi.nlm.nih.gov/pubmed/31686793
http://dx.doi.org/10.2147/NSA.S227193
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author Jahanban-Esfahlan, Rana
Seidi, Khaled
Jahanban-Esfahlan, Ali
Jaymand, Mehdi
Alizadeh, Effat
Majdi, Hasan
Najjar, Reza
Javaheri, Tahereh
Zare, Peyman
author_facet Jahanban-Esfahlan, Rana
Seidi, Khaled
Jahanban-Esfahlan, Ali
Jaymand, Mehdi
Alizadeh, Effat
Majdi, Hasan
Najjar, Reza
Javaheri, Tahereh
Zare, Peyman
author_sort Jahanban-Esfahlan, Rana
collection PubMed
description Among the various nano/biomaterials used in cancer treatment, the beauty and benefits of DNA nanocomposites are outstanding. The specificity and programmability of the base pairing of DNA strands, together with their ability to conjugate with different types of functionalities have realized unsurpassed potential for the production of two- and three-dimensional nano-sized structures in any shape, size, surface chemistry and functionality. This review aims to provide an insight into the diversity of static DNA nanodevices, including DNA origami, DNA polyhedra, DNA origami arrays and bioreactors, DNA nanoswitch, DNA nanoflower, hydrogel and dendrimer as young but promising platforms for cancer theranostics. The utility and potential of the individual formats in biomedical science and especially in cancer therapy will be discussed.
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spelling pubmed-68005572019-11-04 Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications Jahanban-Esfahlan, Rana Seidi, Khaled Jahanban-Esfahlan, Ali Jaymand, Mehdi Alizadeh, Effat Majdi, Hasan Najjar, Reza Javaheri, Tahereh Zare, Peyman Nanotechnol Sci Appl Review Among the various nano/biomaterials used in cancer treatment, the beauty and benefits of DNA nanocomposites are outstanding. The specificity and programmability of the base pairing of DNA strands, together with their ability to conjugate with different types of functionalities have realized unsurpassed potential for the production of two- and three-dimensional nano-sized structures in any shape, size, surface chemistry and functionality. This review aims to provide an insight into the diversity of static DNA nanodevices, including DNA origami, DNA polyhedra, DNA origami arrays and bioreactors, DNA nanoswitch, DNA nanoflower, hydrogel and dendrimer as young but promising platforms for cancer theranostics. The utility and potential of the individual formats in biomedical science and especially in cancer therapy will be discussed. Dove 2019-10-15 /pmc/articles/PMC6800557/ /pubmed/31686793 http://dx.doi.org/10.2147/NSA.S227193 Text en © 2019 Jahanban-Esfahlan et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Jahanban-Esfahlan, Rana
Seidi, Khaled
Jahanban-Esfahlan, Ali
Jaymand, Mehdi
Alizadeh, Effat
Majdi, Hasan
Najjar, Reza
Javaheri, Tahereh
Zare, Peyman
Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications
title Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications
title_full Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications
title_fullStr Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications
title_full_unstemmed Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications
title_short Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications
title_sort static dna nanostructures for cancer theranostics: recent progress in design and applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800557/
https://www.ncbi.nlm.nih.gov/pubmed/31686793
http://dx.doi.org/10.2147/NSA.S227193
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