Isovitexin Suppresses Cancer Stemness Property And Induces Apoptosis Of Osteosarcoma Cells By Disruption Of The DNMT1/miR-34a/Bcl-2 Axis

BACKGROUND: Isovitexin (apigenin-6-C-glucoside, ISOV) is a natural flavonoid that exhibits tumor suppressive activity on various types of cancer. However, it is unknown whether the mechanism of its action in osteosarcoma (OS) is associated with epigenetic regulation and whether it involves DNA methy...

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Detalles Bibliográficos
Autores principales: Liang, Xiao, Xu, Chang, Cao, Xiaocheng, Wang, Wanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800563/
https://www.ncbi.nlm.nih.gov/pubmed/31686915
http://dx.doi.org/10.2147/CMAR.S222708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800563/
https://www.ncbi.nlm.nih.gov/pubmed/31686915
http://dx.doi.org/10.2147/CMAR.S222708

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