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Pregnancy Hypertension and a Commonly Inherited IGF1R Variant (rs2016347) Reduce Breast Cancer Risk by Enhancing Mammary Gland Involution

BACKGROUND: Terminal duct lobular units (TDLUs) are the anatomic sites of breast cancer initiation, and breast tissue involution resulting in lower TDLU counts has been associated with decreased breast cancer risk. The insulin-like growth factor (IGF) pathway plays a role in breast involution, and s...

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Detalles Bibliográficos
Autores principales:	Powell, Mark J., Dufault, Suzanne M., Henry, Jill E., Allison, Anna C., Cora, Renata, Benz, Christopher C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800903/ https://www.ncbi.nlm.nih.gov/pubmed/31687025 http://dx.doi.org/10.1155/2019/6018432

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