Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

BACKGROUND: Intratumor subsets with tumor-initiating features in glioblastoma are likely to survive treatment. Our goal is to identify the key factor in the process by which cells develop temozolomide (TMZ) resistance. METHODS: Resistant cell lines derived from U87MG and A172 were established throug...

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Detalles Bibliográficos
Autores principales: Chien, Chia-Hung, Chuang, Jian-Ying, Yang, Shun-Tai, Yang, Wen-Bin, Chen, Pin-Yuan, Hsu, Tsung-I, Huang, Chih-Yuan, Lo, Wei-Lun, Yang, Ka-Yen, Liu, Ming-Sheng, Chu, Jui-Mei, Chung, Pei-Hsuan, Liu, Jr-Jiun, Chou, Shao-Wen, Chen, Shang-Hung, Chang, Kwang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800988/
https://www.ncbi.nlm.nih.gov/pubmed/31629402
http://dx.doi.org/10.1186/s12929-019-0565-2

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