Systematic optimization for production of the anti‐MRSA antibiotics WAP‐8294A in an engineered strain of Lysobacter enzymogenes

WAP‐8294A is a group of cyclic lipodepsipeptides and considered as the first‐in‐class new chemical entity with potent activity against methicillin‐resistant Staphylococcus aureus. One of the roadblocks in developing the WAP‐8294A antibiotics is the very low yield in Lysobacter. Here, we carried out...

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Detalles Bibliográficos
Autores principales: Chen, Xusheng, Li, Shanren, Yu, Lingjun, Miller, Amanda, Du, Liangcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801147/
https://www.ncbi.nlm.nih.gov/pubmed/31520522
http://dx.doi.org/10.1111/1751-7915.13484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801147/
https://www.ncbi.nlm.nih.gov/pubmed/31520522
http://dx.doi.org/10.1111/1751-7915.13484

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