Prediction Model with High-Performance Constitutive Androstane Receptor (CAR) Using DeepSnap-Deep Learning Approach from the Tox21 10K Compound Library

The constitutive androstane receptor (CAR) plays pivotal roles in drug-induced liver injury through the transcriptional regulation of drug-metabolizing enzymes and transporters. Thus, identifying regulatory factors for CAR activation is important for understanding its mechanisms. Numerous studies co...

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Detalles Bibliográficos
Autores principales: Matsuzaka, Yasunari, Uesawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801383/
https://www.ncbi.nlm.nih.gov/pubmed/31574921
http://dx.doi.org/10.3390/ijms20194855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801383/
https://www.ncbi.nlm.nih.gov/pubmed/31574921
http://dx.doi.org/10.3390/ijms20194855

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