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Angiotensin-II Drives Human Satellite Cells Toward Hypertrophy and Myofibroblast Trans-Differentiation by Two Independent Pathways

Skeletal muscle regeneration is ensured by satellite cells (SC), which upon activation undergo self-renewal and myogenesis. The correct sequence of healing events may be offset by inflammatory and/or fibrotic factors able to promote fibrosis and consequent muscle wasting. Angiotensin-II (Ang) is an...

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Detalles Bibliográficos
Autores principales: Laurino, Annunziatina, Spinelli, Valentina, Gencarelli, Manuela, Balducci, Valentina, Dini, Leonardo, Diolaiuti, Lorenzo, Ghionzoli, Marco, Messineo, Antonio, Mugelli, Alessandro, Cerbai, Elisabetta, Raimondi, Laura, Sartiani, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801484/
https://www.ncbi.nlm.nih.gov/pubmed/31623362
http://dx.doi.org/10.3390/ijms20194912

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