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Overweight: A Protective Factor against Comorbidity in the Elderly
The aim of this study was to investigate the relationship between body mass index (BMI) categories and comorbidity in 9067 patients (age range 18‒94 years) who underwent upper digestive endoscopy in Northern Sardinia, Italy. The majority of participants (62.2%) had a BMI under 25 kg/m(2), overweight...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801595/ https://www.ncbi.nlm.nih.gov/pubmed/31569448 http://dx.doi.org/10.3390/ijerph16193656 |
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author | Pes, Giovanni Mario Licheri, Giulia Soro, Sara Longo, Nunzio Pio Salis, Roberta Tomassini, Giulia Niolu, Caterina Errigo, Alessandra Dore, Maria Pina |
author_facet | Pes, Giovanni Mario Licheri, Giulia Soro, Sara Longo, Nunzio Pio Salis, Roberta Tomassini, Giulia Niolu, Caterina Errigo, Alessandra Dore, Maria Pina |
author_sort | Pes, Giovanni Mario |
collection | PubMed |
description | The aim of this study was to investigate the relationship between body mass index (BMI) categories and comorbidity in 9067 patients (age range 18‒94 years) who underwent upper digestive endoscopy in Northern Sardinia, Italy. The majority of participants (62.2%) had a BMI under 25 kg/m(2), overweight was detected in 30.4%, and obesity (BMI ≥ 30 kg/m(2)) in 7.4% of patients. The most frequent illness recorded was hypertension followed by cardiovascular and liver disease. The multivariate analysis, after adjusting for sex, residence, marital status, smoking habits, occupation and hospitalization detected an association between comorbidity and aging that was statistically significant and progressive. Among patients younger than 60 years (n = 5612) the comorbidity risk was higher for BMI ranging 27.5‒29.9 kg/m(2) compared with BMI 25.0‒27.4 kg/m(2) (RR = 1.38; 95% CI 1.27‒1.50 vs. RR = 0.86; 95% CI 0.81‒0.90). In patients older than 60 years (n= 3455) the risk was lower for a BMI in the range 27.5–29.9 kg/m(2) compared with a BMI in the range 25.0–27.4 kg/m(2) (RR = 1.11; 95% CI 1.05‒1.18 vs. RR = 1.28; 95% CI 1.21‒1.35). These results suggest that being moderately overweight is a marker of a healthy aging process and might protect, at least in part, against comorbidity. However, further research is needed to better understand this unexpected finding. |
format | Online Article Text |
id | pubmed-6801595 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-68015952019-10-31 Overweight: A Protective Factor against Comorbidity in the Elderly Pes, Giovanni Mario Licheri, Giulia Soro, Sara Longo, Nunzio Pio Salis, Roberta Tomassini, Giulia Niolu, Caterina Errigo, Alessandra Dore, Maria Pina Int J Environ Res Public Health Article The aim of this study was to investigate the relationship between body mass index (BMI) categories and comorbidity in 9067 patients (age range 18‒94 years) who underwent upper digestive endoscopy in Northern Sardinia, Italy. The majority of participants (62.2%) had a BMI under 25 kg/m(2), overweight was detected in 30.4%, and obesity (BMI ≥ 30 kg/m(2)) in 7.4% of patients. The most frequent illness recorded was hypertension followed by cardiovascular and liver disease. The multivariate analysis, after adjusting for sex, residence, marital status, smoking habits, occupation and hospitalization detected an association between comorbidity and aging that was statistically significant and progressive. Among patients younger than 60 years (n = 5612) the comorbidity risk was higher for BMI ranging 27.5‒29.9 kg/m(2) compared with BMI 25.0‒27.4 kg/m(2) (RR = 1.38; 95% CI 1.27‒1.50 vs. RR = 0.86; 95% CI 0.81‒0.90). In patients older than 60 years (n= 3455) the risk was lower for a BMI in the range 27.5–29.9 kg/m(2) compared with a BMI in the range 25.0–27.4 kg/m(2) (RR = 1.11; 95% CI 1.05‒1.18 vs. RR = 1.28; 95% CI 1.21‒1.35). These results suggest that being moderately overweight is a marker of a healthy aging process and might protect, at least in part, against comorbidity. However, further research is needed to better understand this unexpected finding. MDPI 2019-09-29 2019-10 /pmc/articles/PMC6801595/ /pubmed/31569448 http://dx.doi.org/10.3390/ijerph16193656 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pes, Giovanni Mario Licheri, Giulia Soro, Sara Longo, Nunzio Pio Salis, Roberta Tomassini, Giulia Niolu, Caterina Errigo, Alessandra Dore, Maria Pina Overweight: A Protective Factor against Comorbidity in the Elderly |
title | Overweight: A Protective Factor against Comorbidity in the Elderly |
title_full | Overweight: A Protective Factor against Comorbidity in the Elderly |
title_fullStr | Overweight: A Protective Factor against Comorbidity in the Elderly |
title_full_unstemmed | Overweight: A Protective Factor against Comorbidity in the Elderly |
title_short | Overweight: A Protective Factor against Comorbidity in the Elderly |
title_sort | overweight: a protective factor against comorbidity in the elderly |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801595/ https://www.ncbi.nlm.nih.gov/pubmed/31569448 http://dx.doi.org/10.3390/ijerph16193656 |
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