The Organogermanium Compound THGP Suppresses Melanin Synthesis via Complex Formation with L-DOPA on Mushroom Tyrosinase and in B16 4A5 Melanoma Cells

The organogermanium compound 3-(trihydroxygermyl)propanoic acid (THGP) has various biological activities. We previously reported that THGP forms a complex with cis-diol structures. L-3,4-Dihydroxyphenylalanine (L-DOPA), a precursor of melanin, contains a cis-diol structure in its catechol skeleton,...

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Detalles Bibliográficos
Autores principales: Azumi, Junya, Takeda, Tomoya, Shimada, Yasuhiro, Aso, Hisashi, Nakamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801725/
https://www.ncbi.nlm.nih.gov/pubmed/31561511
http://dx.doi.org/10.3390/ijms20194785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801725/
https://www.ncbi.nlm.nih.gov/pubmed/31561511
http://dx.doi.org/10.3390/ijms20194785

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