Cargando…
Antitumor Activity of a Novel Tyrosine Kinase Inhibitor AIU2001 Due to Abrogation of the DNA Damage Repair in Non-Small Cell Lung Cancer Cells
Class III receptor tyrosine kinase (RTK) inhibitors targeting mainly FLT3 or c-KIT have not been well studied in lung cancer. To identify a small molecule potentially targeting class III RTK, we synthesized novel small molecule compounds and identified 5-(4-bromophenyl)-N-(naphthalen-1-yl) oxazol-2-...
Autores principales: | Ryu, Hwani, Choi, Hyun-Kyung, Kim, Hyo Jeong, Kim, Ah-Young, Song, Jie-Young, Hwang, Sang-Gu, Kim, Jae-Sung, Kim, Da-Un, Kim, Eun-Ho, Kim, Joon, Ahn, Jiyeon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801739/ https://www.ncbi.nlm.nih.gov/pubmed/31554189 http://dx.doi.org/10.3390/ijms20194728 |
Ejemplares similares
-
Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor
por: Ryu, Hwani, et al.
Publicado: (2021) -
A Small Compound KJ-28d Enhances the Sensitivity of Non-Small Cell Lung Cancer to Radio- and Chemotherapy
por: Ryu, Hwani, et al.
Publicado: (2019) -
Discovery of Oxazol-2-amine Derivatives as Potent Novel FLT3 Inhibitors
por: Kim, Hyo Jeong, et al.
Publicado: (2020) -
134th AIU Colloquium on Nonlinear Phenomena in Stellar Variability
por: Takeuti, M, et al.
Publicado: (1993) -
TGF-β and Hypoxia/Reoxygenation Promote Radioresistance of A549 Lung Cancer Cells through Activation of Nrf2 and EGFR
por: Lee, Sae-lo-oom, et al.
Publicado: (2016)