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Structure and Dynamics of Mono- vs. Doubly Lipidated Rab5 in Membranes
The Rab5 small GTPase is a regulator of endosomal trafficking and vesicle fusion. It possesses two adjacent cysteine residues for post-translational geranylgeranylation at its C-terminus for the protein to associate with the early endosome membrane. We compare the effect of mono-lipidification of on...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801778/ https://www.ncbi.nlm.nih.gov/pubmed/31561436 http://dx.doi.org/10.3390/ijms20194773 |