KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction

Loss-of-function mutations of the gene encoding Krev interaction trapped protein 1 (KRIT1) are associated with the pathogenesis of Cerebral Cavernous Malformation (CCM), a major cerebrovascular disease characterized by abnormally enlarged and leaky capillaries and affecting 0.5% of the human populat...

Descripción completa

Detalles Bibliográficos
Autores principales: Vieceli Dalla Sega, Francesco, Mastrocola, Raffaella, Aquila, Giorgio, Fortini, Francesca, Fornelli, Claudia, Zotta, Alessia, Cento, Alessia S., Perrelli, Andrea, Boda, Enrica, Pannuti, Antonio, Marchi, Saverio, Pinton, Paolo, Ferrari, Roberto, Rizzo, Paola, Retta, Saverio Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801783/
https://www.ncbi.nlm.nih.gov/pubmed/31590384
http://dx.doi.org/10.3390/ijms20194930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801783/
https://www.ncbi.nlm.nih.gov/pubmed/31590384
http://dx.doi.org/10.3390/ijms20194930

Ejemplares similares