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KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction
Loss-of-function mutations of the gene encoding Krev interaction trapped protein 1 (KRIT1) are associated with the pathogenesis of Cerebral Cavernous Malformation (CCM), a major cerebrovascular disease characterized by abnormally enlarged and leaky capillaries and affecting 0.5% of the human populat...
Autores principales: | Vieceli Dalla Sega, Francesco, Mastrocola, Raffaella, Aquila, Giorgio, Fortini, Francesca, Fornelli, Claudia, Zotta, Alessia, Cento, Alessia S., Perrelli, Andrea, Boda, Enrica, Pannuti, Antonio, Marchi, Saverio, Pinton, Paolo, Ferrari, Roberto, Rizzo, Paola, Retta, Saverio Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801783/ https://www.ncbi.nlm.nih.gov/pubmed/31590384 http://dx.doi.org/10.3390/ijms20194930 |
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