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Cardiovascular biomarkers in patients with acute decompensated heart failure randomized to sacubitril-valsartan or enalapril in the PIONEER-HF trial

AIMS: Circulating high-sensitivity cardiac troponin (hsTn) and soluble ST2 (sST2) reflect myocardial stress in patients with heart failure (HF). Production of cyclic guanosine 3′5′ monophosphate (cGMP) in response to activation of natriuretic peptide receptors reduces cardiac afterload and preload....

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Detalles Bibliográficos
Autores principales:	Morrow, David A, Velazquez, Eric J, DeVore, Adam D, Prescott, Margaret F, Duffy, Carol I, Gurmu, Yared, McCague, Kevin, Rocha, Ricardo, Braunwald, Eugene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Fast Track Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801941/ https://www.ncbi.nlm.nih.gov/pubmed/31093657 http://dx.doi.org/10.1093/eurheartj/ehz240

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