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Study designs: Part 5 – interventional studies (II)

In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention). In this article, we take a closer look at several fe...

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Detalles Bibliográficos
Autores principales: Aggarwal, Rakesh, Ranganathan, Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801992/
https://www.ncbi.nlm.nih.gov/pubmed/31649869
http://dx.doi.org/10.4103/picr.PICR_138_19
Descripción
Sumario:In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention). In this article, we take a closer look at several features which are important to ensure that the findings of such a study represent the real effect of an intervention, such as allocation concealment, blinding, compliance to intervention, the use of co-interventions and participant dropout rate.