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Study designs: Part 5 – interventional studies (II)
In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention). In this article, we take a closer look at several fe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801992/ https://www.ncbi.nlm.nih.gov/pubmed/31649869 http://dx.doi.org/10.4103/picr.PICR_138_19 |
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author | Aggarwal, Rakesh Ranganathan, Priya |
author_facet | Aggarwal, Rakesh Ranganathan, Priya |
author_sort | Aggarwal, Rakesh |
collection | PubMed |
description | In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention). In this article, we take a closer look at several features which are important to ensure that the findings of such a study represent the real effect of an intervention, such as allocation concealment, blinding, compliance to intervention, the use of co-interventions and participant dropout rate. |
format | Online Article Text |
id | pubmed-6801992 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-68019922019-10-24 Study designs: Part 5 – interventional studies (II) Aggarwal, Rakesh Ranganathan, Priya Perspect Clin Res Statistics In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention). In this article, we take a closer look at several features which are important to ensure that the findings of such a study represent the real effect of an intervention, such as allocation concealment, blinding, compliance to intervention, the use of co-interventions and participant dropout rate. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6801992/ /pubmed/31649869 http://dx.doi.org/10.4103/picr.PICR_138_19 Text en Copyright: © 2019 Perspectives in Clinical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Statistics Aggarwal, Rakesh Ranganathan, Priya Study designs: Part 5 – interventional studies (II) |
title | Study designs: Part 5 – interventional studies (II) |
title_full | Study designs: Part 5 – interventional studies (II) |
title_fullStr | Study designs: Part 5 – interventional studies (II) |
title_full_unstemmed | Study designs: Part 5 – interventional studies (II) |
title_short | Study designs: Part 5 – interventional studies (II) |
title_sort | study designs: part 5 – interventional studies (ii) |
topic | Statistics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801992/ https://www.ncbi.nlm.nih.gov/pubmed/31649869 http://dx.doi.org/10.4103/picr.PICR_138_19 |
work_keys_str_mv | AT aggarwalrakesh studydesignspart5interventionalstudiesii AT ranganathanpriya studydesignspart5interventionalstudiesii |