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Study designs: Part 5 – interventional studies (II)

In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention). In this article, we take a closer look at several fe...

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Detalles Bibliográficos
Autores principales: Aggarwal, Rakesh, Ranganathan, Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801992/
https://www.ncbi.nlm.nih.gov/pubmed/31649869
http://dx.doi.org/10.4103/picr.PICR_138_19
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author Aggarwal, Rakesh
Ranganathan, Priya
author_facet Aggarwal, Rakesh
Ranganathan, Priya
author_sort Aggarwal, Rakesh
collection PubMed
description In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention). In this article, we take a closer look at several features which are important to ensure that the findings of such a study represent the real effect of an intervention, such as allocation concealment, blinding, compliance to intervention, the use of co-interventions and participant dropout rate.
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spelling pubmed-68019922019-10-24 Study designs: Part 5 – interventional studies (II) Aggarwal, Rakesh Ranganathan, Priya Perspect Clin Res Statistics In the fifth piece of this series on research study designs, we continue the discussion on interventional studies (clinical trials), in which the investigator decides whether or not a particular participant receives the exposure (or intervention). In this article, we take a closer look at several features which are important to ensure that the findings of such a study represent the real effect of an intervention, such as allocation concealment, blinding, compliance to intervention, the use of co-interventions and participant dropout rate. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6801992/ /pubmed/31649869 http://dx.doi.org/10.4103/picr.PICR_138_19 Text en Copyright: © 2019 Perspectives in Clinical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Statistics
Aggarwal, Rakesh
Ranganathan, Priya
Study designs: Part 5 – interventional studies (II)
title Study designs: Part 5 – interventional studies (II)
title_full Study designs: Part 5 – interventional studies (II)
title_fullStr Study designs: Part 5 – interventional studies (II)
title_full_unstemmed Study designs: Part 5 – interventional studies (II)
title_short Study designs: Part 5 – interventional studies (II)
title_sort study designs: part 5 – interventional studies (ii)
topic Statistics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801992/
https://www.ncbi.nlm.nih.gov/pubmed/31649869
http://dx.doi.org/10.4103/picr.PICR_138_19
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