Concatenation of 14-3-3 with partner phosphoproteins as a tool to study their interaction

Regulatory 14-3-3 proteins interact with a plethora of phosphorylated partner proteins, however 14-3-3 complexes feature intrinsically disordered regions and often a transient type of interactions making structural studies difficult. Here we engineer and examine a chimera of human 14-3-3 tethered to...

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Detalles Bibliográficos
Autores principales: Tugaeva, Kristina V., Kalacheva, Daria I., Cooley, Richard B., Strelkov, Sergei V., Sluchanko, Nikolai N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802120/
https://www.ncbi.nlm.nih.gov/pubmed/31628352
http://dx.doi.org/10.1038/s41598-019-50941-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802120/
https://www.ncbi.nlm.nih.gov/pubmed/31628352
http://dx.doi.org/10.1038/s41598-019-50941-3

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