Cargando…
The Neuroprotective Effects of Necrostatin-1 on Subarachnoid Hemorrhage in Rats Are Possibly Mediated by Preventing Blood–Brain Barrier Disruption and RIP3-Mediated Necroptosis
Despite the substantial efforts to elucidate the role of early brain injury in subarachnoid hemorrhage (SAH), an effective pharmaceutical therapy for patients with SAH continues to be unavailable. This study aims to reveal the role of necroptosis after SAH, and explore whether the disruption of the...
Autores principales: | Chen, Jingsen, Jin, Hanghuang, Xu, Hangzhe, Peng, Yucong, Jie, Liyong, Xu, Demin, Chen, Lili, Li, Tao, Fan, Linfeng, He, Pingyou, Ying, Guangyu, Gu, Chi, Wang, Chun, Wang, Lin, Chen, Gao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802141/ https://www.ncbi.nlm.nih.gov/pubmed/31370690 http://dx.doi.org/10.1177/0963689719867285 |
Ejemplares similares
-
Celastrol protects against early brain injury after subarachnoid hemorrhage in rats through alleviating blood-brain barrier disruption and blocking necroptosis
por: Xu, Hangzhe, et al.
Publicado: (2021) -
RIP3‐mediated necroptosis increases neuropathic pain via microglia activation: necrostatin‐1 has therapeutic potential
por: Fang, Ping, et al.
Publicado: (2021) -
Necroptosis, necrostatins and tissue injury
por: Smith, Christopher CT, et al.
Publicado: (2011) -
Necrostatin-1 attenuates early brain injury after subarachnoid hemorrhage in rats by inhibiting necroptosis
por: Chen, Fuxiang, et al.
Publicado: (2017) -
Inhibition of neuronal necroptosis mediated by RIP1/RIP3/MLKL provides neuroprotective effects on kaolin‐induced hydrocephalus in mice
por: Liu, Chang, et al.
Publicado: (2021)