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Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice

Fibroblast Growth Factor 23 (FGF23) is a phosphaturic factor causing increased renal phosphate excretion as well as suppression of 1,25 (OH)(2)-vitamin D(3.) Highly elevated FGF23 can promote development of rickets and osteomalacia. We and others previously reported that acute application of erythro...

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Detalles Bibliográficos
Autores principales: Daryadel, Arezoo, Natale, Luciano, Seebeck, Petra, Bettoni, Carla, Schnitzbauer, Udo, Gassmann, Max, Wagner, Carsten A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802194/
https://www.ncbi.nlm.nih.gov/pubmed/31628396
http://dx.doi.org/10.1038/s41598-019-51577-z