Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells

In the human hematopoietic system, rare self-renewing multipotent long-term hematopoietic stem cells (LT-HSCs) are responsible for the lifelong production of mature blood cells and are the rational target for clinical regenerative therapies. However, the heterogeneity in the hematopoietic stem cell...

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Detalles Bibliográficos
Autores principales: Wagenblast, Elvin, Azkanaz, Maria, Smith, Sabrina A., Shakib, Lorien, McLeod, Jessica L., Krivdova, Gabriela, Araújo, Joana, Shultz, Leonard D., Gan, Olga I., Dick, John E., Lechman, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802205/
https://www.ncbi.nlm.nih.gov/pubmed/31628330
http://dx.doi.org/10.1038/s41467-019-12726-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802205/
https://www.ncbi.nlm.nih.gov/pubmed/31628330
http://dx.doi.org/10.1038/s41467-019-12726-0

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