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Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(−/−) mice on a high-fat, high-cholesterol diet

While the link between diet-induced changes in gut microbiota and lipid metabolism in metabolic syndrome (MetS) has been established, the contribution of host genetics is rather unexplored. As several findings suggested a role for the lysosomal lipid transporter Niemann-Pick type C1 (NPC1) in macrop...

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Detalles Bibliográficos
Autores principales:	Houben, Tom, Penders, John, Oligschlaeger, Yvonne, dos Reis, Inês A. Magro, Bonder, Marc-Jan, Koonen, Debby P., Fu, Jingyuan, Hofker, Marten H., Shiri-Sverdlov, Ronit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802207/ https://www.ncbi.nlm.nih.gov/pubmed/31628414 http://dx.doi.org/10.1038/s41598-019-51525-x

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