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Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods
BACKGROUND: Accurate fusion transcript detection is essential for comprehensive characterization of cancer transcriptomes. Over the last decade, multiple bioinformatic tools have been developed to predict fusions from RNA-seq, based on either read mapping or de novo fusion transcript assembly. RESUL...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802306/ https://www.ncbi.nlm.nih.gov/pubmed/31639029 http://dx.doi.org/10.1186/s13059-019-1842-9 |