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Microbial biofilm correlates with an increased antibiotic tolerance and poor therapeutic outcome in infective endocarditis

BACKGROUND: Infective endocarditis (IE) is associated with high rates of mortality. Prolonged treatments with high-dose intravenous antibiotics often fail to eradicate the infection, frequently leading to high-risk surgical intervention. By providing a mechanism of antibiotic tolerance, which escape...

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Detalles Bibliográficos
Autores principales:	Di Domenico, Enea Gino, Rimoldi, Sara Giordana, Cavallo, Ilaria, D’Agosto, Giovanna, Trento, Elisabetta, Cagnoni, Giovanni, Palazzin, Alessandro, Pagani, Cristina, Romeri, Francesca, De Vecchi, Elena, Schiavini, Monica, Secchi, Daniela, Antona, Carlo, Rizzardini, Giuliano, Dichirico, Rita Barbara, Toma, Luigi, Kovacs, Daniela, Cardinali, Giorgia, Gallo, Maria Teresa, Gismondo, Maria Rita, Ensoli, Fabrizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802308/ https://www.ncbi.nlm.nih.gov/pubmed/31638894 http://dx.doi.org/10.1186/s12866-019-1596-2

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